Enhancing MicroRNA Activity through Increased Endosomal Release Mediated by Nigericin
The therapeutic promise of small-RNA therapeutics is limited, not only by the lack of delivery vehicles, but also by the inability of iPad Case the small RNAs to reach intracellular compartments where they can be biologically active.We previously reported successful delivery of functionally active miRNAs via receptor-mediated endocytosis.This type